MSK Doctors Research completed studies and published evidence
Completed Studies & Programmes

Evidence That
Compounds Over Time.

Our completed studies and competitively-funded programmes form the published foundation beneath every active research initiative — spanning ten-year arthroplasty follow-up, AI-enabled motion analysis, and internationally-recognised digital health innovation.

10

Completed Programmes

10yr

Longest Follow-Up

£480k

Innovate UK Funding

Top 10

Santander X 2025

Programme Library

10 Completed Chapters in a Continuing Programme.

Filter by year, type of evidence or topic. Each completed study feeds directly into the active and upcoming programmes.

Showing 10 of 10 studies

3-Repetition Squat Validation
Completed

Cureus 2026

Protocol ValidationPeer-Reviewed · 2026

3-Repetition Squat Validation

Empirical Validation Using MAI Motion

A peer-reviewed pilot testing whether three squat repetitions capture the same biomechanics as the conventional five. Across 52 kinematic parameters in 10 adults, no mean differed significantly — and the three-rep protocol was fractionally the more consistent of the two.

No significant difference across 52 parameters between 3 and 5 squat reps

Cohort

10 Adults

Reduction

5 → 3 Reps

Parameters

52

Read the completed-study briefView Study
UniReliever® Knee Brace
Completed

Cureus 2026

Digital BiomechanicsPeer-Reviewed · 2026

UniReliever® Knee Brace

Dynamic Offloading Measured with MAI Motion

A within-participant biomechanical study of adults with knee osteoarthritis, using the markerless MAI Motion platform to compare no brace, an inactive brace and active offloading during sit-to-stand and squat — showing that objective measurement can distinguish wearing a brace from engaging its offloading.

Objective capture distinguished active offloading from an inactive brace

Cohort

8 Adults

Conditions

3 Brace

Capture

Markerless

Read the completed-study briefView Study
Polyacrylamide Hydrogel for Knee Osteoarthritis
Completed

24-Month Cohort

Injection TherapyPeer-Reviewed · 2025

Polyacrylamide Hydrogel for Knee Osteoarthritis

A PROMs-Based 24-Month Prospective Cohort Study

A prospective cohort tracking patient-reported outcomes across 314 osteoarthritic knees for two years after polyacrylamide hydrogel (PAAG) injection — identifying which patients gain the most durable benefit from this minimally invasive treatment.

314 knees tracked with three PROMs over 24 months after PAAG injection

Cohort

314 Knees

Follow-Up

24 Months

Outcomes

3 PROMs

Read the completed-study briefView Study
Motion-Based Biomarkers in Knee Disorders
Completed

Front. Digit. Health 2024

Biomarker DiscoveryPeer-Reviewed · 2024

Motion-Based Biomarkers in Knee Disorders

A Marker-less Human Motion Analysis System

A peer-reviewed study that turns ordinary RGB video into objective motion-based biomarkers — using 3D mesh recovery and principal component analysis to find which movement features change measurably after a knee injection, validated against pre- and post-treatment data from 20 adults with knee pain.

Single-camera motion biomarkers changed measurably after knee injection

Cohort

20 Adults

Actions

Squat + STS

Capture

Single RGB

Read the completed-study briefView Study
Marker-less Motion Capture in Knee Osteoarthritis
Completed

J Arthritis 2022

Motion Capture ValidationPeer-Reviewed · 2022

Marker-less Motion Capture in Knee Osteoarthritis

A Low-Cost Human Motion Analysis Method

The foundational study comparing marker-less RGB-D capture against the marker-based Knee Kinesiography system during treadmill gait — showing that strapping hardware to the leg suppresses knee flexion range by 10–15°, and that marker-less capture measures walking closer to how it naturally happens.

Leg-mounted hardware suppressed knee flexion range by 10–15°

Capture

2 × RGB-D

Flexion Gain

10–15°

Comparator

KneeKG

Read the completed-study briefView Study

Continuing Forward

Completion is not an endpoint.
It is progression.

Long-term data strengthens today’s decisions. Ongoing evaluation strengthens tomorrow’s. Explore the active research programmes that build directly on the work completed here.

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