Clinical research team in active study planning meeting

Ongoing Research · Currently Enrolling

Active Studies,
Real Patients.

These are the clinical programmes we are running today — focused on long-term patient outcomes, innovative implant technology, and rigorous evaluation of digital and non-pharmacological therapies in UK orthopaedic care.

Active Studies

Patient Focus

10yr

Longest Horizon

Currently Enrolling

4 studies, 2 taking
UK participants now.

Filter by approval year, enrolment status, body area or study design. Each card carries the research ethics committee approval for that study.

Showing 4 of 4 studies

MSK Injection Therapies Outcomes & Safety Study

HRA Approved

Observational cohort

Injection TherapyNewly approved

MSK Injection Therapies Outcomes & Safety Study

Prospective observational cohort · routine care

A prospective observational cohort study following patients who receive musculoskeletal injection therapies as part of routine care at MSK Doctors, recording their outcomes and any safety events over time without changing their treatment.

Real-world outcomes and safety of injection therapies, approved 8 September 2026

Design

Observational

Setting

Routine Care

IRAS ID

375544

Ethics approval for MSK Injection Therapies Outcomes & Safety Study

Ethics approvalREC 26SW0096 · IRAS 375544 · approved 2026

Patients receiving musculoskeletal injection therapy as routine care at MSK Doctors may be invited to take part.Study Details

Enrolling

Controlled study

Recovery ScienceActive

Regen EMS™ Quadriceps Recovery Study

Prospective controlled study · 6-week tracking

A prospective controlled clinical study exploring whether targeted, non-invasive electrical muscle stimulation can reduce early quadriceps wasting and support functional recovery after knee surgery.

Six-week tracking of quadriceps wasting after knee surgery, with and without EMS

Methodology

Non-Invasive EMS

Focus Area

Muscular Atrophy

Lead Partner

MSK Research Lab

Ethics approval for Regen EMS™ Quadriceps Recovery Study

Ethics approvalREC 26WM0063 · approved 2026

Eligible for patients undergoing knee surgery within the MSK Doctors network.Study Details

U2 Mobile Bearing (MB™) Total Knee Replacement Follow-up

Enrolling

Non-interventional follow-up

Knee ArthroplastyActive

U2 Mobile Bearing (MB™) Total Knee Replacement Follow-up

Prospective non-interventional · 10-year tracking

Tracking real-world function, implant integrity, and patient-reported outcomes over 10 years following U2 MB™ knee replacement — a contemporary mobile-bearing system used in UK orthopaedic practice.

Ten-year follow-up of function, implant integrity and patient-reported outcomes

Follow-up

10 Years

Design

Non-Interventional

Population

UK Focus

Ethics approval for U2 Mobile Bearing (MB™) Total Knee Replacement Follow-up

Ethics approvalREC 25WM0048 · IRAS 345483 · approved 2025

Eligible for patients with completed or planned U2 MB™ knee replacement.Study Details

Incrediwear™ Achilles Tendon Treatment Study

Paused

Clinical pathway

Sports MedicinePaused

Incrediwear™ Achilles Tendon Treatment Study

Structured 24-week pathway · drug-free therapy

A structured 24-week clinical pathway evaluating non-compressive, drug-free therapy for Achilles tendinopathy, including serial open MRI imaging and standardised functional monitoring.

24-week drug-free pathway with two open MRI scans and functional monitoring

Protocol

24 Weeks

Imaging

2 Open MRIs

Therapy

100% Drug-Free

Ethics approval for Incrediwear™ Achilles Tendon Treatment Study

Ethics approvalREC 25PR0953 · IRAS 359872 · approved 2025

Enrolment is currently paused — not accepting new participants at this time.Study Details

The Wider Programme

Today’s evidence, tomorrow’s standard.

Active enrolment is one chapter. See the published evidence base behind it, and the upcoming programmes already in preparation for launch.

Completed Studies Upcoming Programmes

Active Studies, Real Patients.